Neuroimaging biomarkers and impaired olfaction in cognitively normal individuals
نویسندگان
چکیده
منابع مشابه
Nutrient intake and brain biomarkers of Alzheimer's disease in at-risk cognitively normal individuals: a cross-sectional neuroimaging pilot study
OBJECTIVE There is increasing evidence to suggest that diet, one of the most important modifiable environmental factors, may play a role in preventing or delaying cognitive decline and Alzheimer's disease (AD). This study examines the relationship between dietary nutrients and brain biomarkers of AD in cognitively normal individuals (NL) with and without AD risk factors. DESIGN As part of an ...
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Introduction A major challenge in designing technology for users with cognitive impairments is achieving generalizable results. By design, controlled experiments—the gold standard of evaluation in HCI research—remove individual differences through statistical means. While this is appropriate in many situations, when working with special populations, individual differences are often very pronoun...
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Technological advances have led to greater use of both structural and functional brain imaging to assist with the diagnosis of dementia for the increasing numbers of people with cognitive decline as they age. In current clinical practice, structural imaging (CT or MRI) is used to identify space-occupying lesions and stroke. Functional methods, such as PET scanning of glucose metabolism, could b...
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Cognitive and functional losses are only part of the spectrum of disability experienced by persons with Alzheimer's disease and related dementias. They also experience losses in the ability to make decisions, known as decision-making capacity. Researchers have made substantial progress in developing a model of capacity assessment that rests upon the concept of the 4 decision-making abilities: u...
متن کاملExercise and Alzheimer's disease biomarkers in cognitively normal older adults.
OBJECTIVE In addition to the increasingly recognized role of physical exercise in maintaining cognition, exercise may influence Alzheimer's disease (AD) pathology, as transgenic mouse studies show lowered levels of AD pathology in exercise groups. The objective of this study was to elucidate the association between exercise and AD pathology in humans using Pittsburgh compound-B (PIB), amyloid-b...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2017
ISSN: 0364-5134
DOI: 10.1002/ana.24960